Significance of Atypical Small Acinar Proliferation (ASAP) in Prostate needle biopsy

25/05/09

Many time while reporting prostate needle biopsy, we come across features, which are suspicious for malignancy, but hinder a definitive diagnosis of carcinoma, because of concern about over diagnosis. These are the cases, which are labelled as ASAP, -atypical small acinar proliferation.Diagnostic criteria for ASAP :For pathologists, 3 questions need to be answered before the diagnosis of cancer in a small lesion:â?¢ Would you be absolutely confident of this biopsy diagnosis if it were followed by a negative radical prostatectomy?â?¢ Would another colleague pathologist agree with the diagnosis of cancer?â?¢ Can you confidently support the diagnosis of adenocarcinoma based solely on this biopsy?If the answer to any of these questions is â??No,â? then use of the more conservative diagnosis o…

Original post by Oncopathology and software by Elliott Back

 

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