Many time while reporting prostate needle biopsy, we come across features, which are suspicious for malignancy, but hinder a definitive diagnosis of carcinoma, because of concern about over diagnosis. These are the cases, which are labelled as ASAP, -atypical small acinar proliferation.Diagnostic criteria for ASAP :For pathologists, 3 questions need to be answered before the diagnosis of cancer in a small lesion:â?¢ Would you be absolutely confident of this biopsy diagnosis if it were followed by a negative radical prostatectomy?â?¢ Would another colleague pathologist agree with the diagnosis of cancer?â?¢ Can you confidently support the diagnosis of adenocarcinoma based solely on this biopsy?If the answer to any of these questions is â??No,â? then use of the more conservative diagnosis o…

Original post by Oncopathology and software by Elliott Back

Many time while reporting prostate needle biopsy, we come across features, which are suspicious for malignancy, but hinder a definitive diagnosis of carcinoma, because of concern about over diagnosis. These are the cases, which are labelled as ASAP, -atypical small acinar proliferation.Diagnostic criteria for ASAP :For pathologists, 3 questions need to be answered before the diagnosis of cancer in a small lesion:â?¢ Would you be absolutely confident of this biopsy diagnosis if it were followed by a negative radical prostatectomy?â?¢ Would another colleague pathologist agree with the diagnosis of cancer?â?¢ Can you confidently support the diagnosis of adenocarcinoma based solely on this biopsy?If the answer to any of these questions is â??No,â? then use of the more conservative diagnosis o…

Original post by Oncopathology and software by Elliott Back